Join us to study ion channel structure and function using a combination of cryo-electron microscopy and other biophysical methods. Our lab is based at the Walther Straub Institute of Pharmacology & Toxicology, right in the center of Munich. The institute belongs to the Faculty of Medicine of LMU Munich.
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Prof. Arthur Neuberger, Ph.D.
Professor of Molecular BioImaging
Elite Network Bavaria | Group Leader
Walther Straub Institute of Pharmacology & Toxicology | Faculty of Medicine
LMU Munich
You will clone various human ion channels and optimize their expression and purification with the goal to purify functional, high-purity and -quality channel proteins for cryo-EM and other biophysical experiments (such as single-channel recordings).
You will make cryo-EM preparations and screen these using either cryo-EM or negative-stain EM (our lab owns a transmission electron microscope for in-house screening).
You will select the best specimens for cryo-EM data collection and then process the data to high-resolution maps.
You will use these maps to build molecular structural models.
Using this data, you will write manuscripts for publication in high-impact peer-reviewed scientific journals.
You will present your data at conferences.
We are looking for hard-working scientists (PhD students and postdocs) to join our lab - ideally with prior experience in mammalian cell culture work, molecular biology, protein biochemistry and/or structural biology (of any sort). We are a newly established lab with easy access to any needed cryo-EM preparation tool (provided by our lab) as well as to cryo-EM screening (on our own microscope) and collection facilities (short public transport ride away). Live in one of Europe's most vibrant cities whilst conducting research at the top-ranked university in Germany (ARWU Shanghai Ranking 2024). The compensation is based on TV-L group 13 (see also Entgelttabelle des Tarifsvertrags der Länder, with levels to be determined based on applicant’s expertise).
For a quick overview of the pi’s previous work:
https://scholar.google.com/citations?hl=en&user=ZufZ4T0AAAAJ&view_op=list_works&sortby=pubdate
https://orcid.org/0000-0002-7744-6559
People with disabilities who are equally as qualified as other applicants will receive preferential treatment.