The Leibniz Graduate School on Aging and Age-Related Diseases (LGSA) is a joint program of the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) and the Friedrich Schiller University (FSU) in Jena. The School calls for applications for a PhD position in the research group “Transcriptional control of tissue homeostasis” led by Björn von Eyß.
The Leibniz Graduate School on Aging and Age-Related Diseases (LGSA) belongs to the Leibniz Association - a non-university research organization equivalent to the Max Planck Society and the Helmholtz Association. The von Eyß Research Group studies the Hippo pathway and its impact on organ regeneration, cancer and aging. This signaling pathway has two effector proteins: the transcriptional coactivators YAP and TAZ. The research group focuses on different aspects of the biology of YAP/TAZ. The goal is to identify novel signaling pathways that control YAP/TAZ activity.
We are looking for a highly motivated PhD candidate interested in molecular biology, biochemistry and cell biology techniques as well as basic bioinformatics. The position should be filled as soon as possible.
The project:
The DFG funded research project aims to explore the “decoding of the cytoplasmic role of YAP/TAZ in cancer mechanotransduction”
• Investigation of the role of YAP/TAZ in mechanotransduction
• Identification of cytoplasmic signalling cues that are influenced by YAP/TAZ in a new mouse model
• Characterisation of the mechanisms by which YAP/TAZ are regulated in cytoplasmic signalling pathways Requirements:
Eligible are students that have obtained, or that will obtain in the next months an academic degree comparable to the master degree or diploma in Biology, Life Science, Biomedicine, or equivalent.
Further requirements are:
• Excellent written and verbal communication skills in English We offer:
• A position in a well-equipped and motivated group that aims to bridge wet and dry lab research.
• A highly cooperative environment and possibilities of international collaborations.
• Access to multiple state-of-the-art facilities. Our work is embedded in the Beutenberg Campus, an interdisciplinary base for innovative research.
• Flexible working time, a family friendly working environment including support for child care solutions and dual career.