The University of Marburg, founded in 1527, offers a variety of excellent programs of study for around 22,000 students and confronts the important topics of our time through excellent research across a broad spectrum of sciences.
The Department of Medicine, Core Facility Metabolomics, AG Verena Taudte, invites applications for a
Doctoral Researcher/PhD (m/f/d)
The position is offered for a period of 3 years, if no former times of qualification must be considered. The starting date is as soon as possible. The position is part-time (65 % of regular working hours) with salary and benefits commensurate with a public service position in the state Hesse, Germany (TV-H E 13, 65 %).
The DFG funded graduate school GRK 2573/2 “The inflammatory tumor secretome - from understanding to novel therapies” is initiated by scientists from the Universities of Marburg and Giessen. This research training group GRK 2573 with a focus on the role of the tumor secretome in tumor progression and therapy resistance is characterized by its interdisciplinary composition of basic research-oriented as well as clinicllay active scientists. The inclusion of different tumor entities enables competitive research activity in the field of tumor secretome.
The project is part of the GRK 2573/2 and a collaborative research effort involving the AG Verena Taudte (research focus on metabolomics) and the AG Niklas Gremke (biological/ translational focus). The project investigates the role of metabolic alterations in therapy resistance and tumor-stroma crosstalk in breast cancer, with the aim of uncovering new therapeutic targets.
Prof. Taudte's research group is working on mass spectrometry-based metabolomics. The focus here is on intercellular communication via metabolites within the tumor microenvironment and how this influences the function and plasticity of cells. Samples are obtained using molecular biological methods from AG Gremke and analyzed using state-of-the-art mass spectrometric methods. We are looking for a highly motivated doctoral student to join our dynamic team and bring a great interest and enjoyment to translational biomedical research.
scientific services in research
state-of-the-art investigation of metabolic dysregulations in the tumor microenvironment
establish sample preparation protocols and subsequent state-of-the-art mass spectrometric methods (LC-MS and GC-MS) for targeted and untargeted metabolomics, as well as flux analyses of cell culture and mouse models
investigate metabolic alterations within therapy-resistent breast cancer cells and their secretome as well as the effects of dysregulated metabolites on the tumor microenvironment using the established metabolomics/flux workflows
biological interpretation of the results
active participation in GRK activities, conferences and seminars
The position is limited to a time period deemed adequate for the completion of a doctoral degree. As part of the assigned duties, there will be ample opportunity to conduct the independent scientific research necessary for the completion of a doctorate. The limitation complies to § 2, 1 WissZeitVG.
scientific services in research
state-of-the-art investigation of metabolic dysregulations in the tumor microenvironment
establish sample preparation protocols and subsequent state-of-the-art mass spectrometric methods (LC-MS and GC-MS) for targeted and untargeted metabolomics, as well as flux analyses of cell culture and mouse models
investigate metabolic alterations within therapy-resistent breast cancer cells and their secretome as well as the effects of dysregulated metabolites on the tumor microenvironment using the established metabolomics/flux workflows
biological interpretation of the results
active participation in GRK activities, conferences and seminars
The position is limited to a time period deemed adequate for the completion of a doctoral degree. As part of the assigned duties, there will be ample opportunity to conduct the independent scientific research necessary for the completion of a doctorate. The limitation complies to § 2, 1 WissZeitVG.
an interesting and broad range of skills with many opportunities for your own further developmentan exciting and motiviting work environment
attractive remuneration according to TV Hessen
ticket for free use of public transport in Hesse (Landesticket)