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The INM – Leibniz Institute for New Materials in Saarbrücken, Germany, is an internationally leading center for materials research, a scientific partner to national and international research institutions, and a provider of research and development for companies throughout the world. The INM is an institute of the Leibniz Association and has about 250 employees.
MASTER THESIS: BIOMECHANICAL CHARACTERIZATION OF 3D CANCER CULTURES AND SYNTHETIC CELLS (F/M/D)
* Full or Part Time
* Campus, Saarbrücken
* Without Professional Experience
* 11/21/24
INM’s research group Immuno-Materials combines expertise from synthetic biology, biomaterials and immunology to develop new approaches for studying and regulating immune reactions.
Are you a master student (f/m/d) with a background in cell biology, biomaterials or biophysics (or related fields) and looking for a thesis project? This might be something for you!
Master Thesis: Biomechanical Characterization of 3D CANCER CULTURES and Synthetic Cells (F/M/D)
Starting on March 1st, 2025 (with flexibility).
We have pioneered the development of hybrid 3D cancer cultures formed from pancreatic cancer cells and synthetic cells. This approach can be applied to form artificial tumor immune microenvironments with defined properties and systematically study evasion mechanisms of cancer in immunotherapy. We are able to induce specific molecular and biophysical changes in the cancer cells that reduce the impact of immunotherapy. The master thesis should study the effects on the mechanical properties on both single cell and tissue level as well as the impact of specific immuno-modulators on tumor tissue organization.
Techniques applied include:
* 3D cancer cell culture
* immuno-staining
* advanced microscopy (light-sheet microscopy, confocal fluorescence microscopy)
* indentation analysis and real-time deformation cytometry
Interested? We are looking forward to receiving your application (CV, B.Sc. certificate or transcripts of record, motivation letter) by December 16th, 2024. Please send it via conveniently via our online applications system (single pdf file < 5 MB).
The INM practices an open and appreciative corporate culture in which the existing diversity is promoted and lived. The institute is an equal opportunity employer with a certified family-friendly policy, and it provides offers for a better work-life balance, flextime, and mobile working. We promote professional opportunities for women and strongly encourage them to apply. Severely disabled applicants with equal qualifications and aptitude will be given preferential consideration.
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