Scientist - Genome Engineering
We are seeking a scientist to join our team in the field of genome engineering. The ideal candidate will be part of a growing start-up company that develops innovative disease models and cell therapies by editing and differentiating human induced pluripotent stem cells (hiPSC) into relevant cells of interest.
Responsibilities:
* Lead and contribute to genome engineering projects utilizing advanced gene-editing technologies such as CRISPR/Cas9, base editing, and prime editing.
* Analyze and interpret genomic data employing molecular and cell biology techniques.
* Design, execute, and optimize experiments in stem cell biology, including iPSC culture, differentiation, and characterization.
* Contribute to the generation of master cell banks under GMP conditions.
* Manipulate human cells by various nucleic acid delivery techniques.
* Critically analyze and interpret data, defining realistic timelines for studies.
* Work closely with internal teams and communicate results to external partners.
Qualifications:
* Ph.D. in Molecular Biology, Genetics, Stem Cell Biology, or a related field.
* Proven expertise in genome engineering projects, including CRISPR-based gene editing.
* Preferably a background in stem cell biology, including hands-on experience with iPSC culture and differentiation.
* Good command of English and German.
Our Offer:
We offer the opportunity to contribute to the development of a new research company in an interdisciplinary team with a pioneering spirit. You will be involved in exciting tasks and personal development. Salary is based on qualifications and professional experience, calculated according to civil service salary scales (TVL). The position is initially for two years with the possibility of a permanent extension.
ISAR Bioscience GmbH is a translational research company near Munich, supported by the Free State of Bavaria. Our research focuses on (auto-)immune diseases, degenerative brain diseases (Alzheimer's), and heart diseases. We use human induced pluripotent stem cell (iPSC) technologies to develop disease models for novel drug discovery and cell therapies, entering into strategic partnerships with research institutions and industrial companies.