Application deadline: December 15, 2024 The University Hospital Würzburg is seeking a motivated and talented PhD student (m/f/div) to join the Emmy Noether Research Group led by Dr. Zoltan Nagy at the Institute of Experimental Biomedicine. Be part of a dynamic research group and investigate fundamental mechanisms in hematology In this DFG-funded project, you will work at the forefront of megakaryocyte biology, leveraging state-of-the-art technologies, including single-cell transcriptomics, CRISPR gene editing, transgenic mouse models, and advanced imaging techniques. PhD Position (m/f/div) in Megakaryocyte Biology designing and performing single-cell RNA sequencing experiments, applying advanced data analysis to identify novel regulatory mechanisms conducting in vivo studies in mouse models, focusing on experimental hematology techniques to investigate and modulate platelet biogenesis carrying out in vitro cell culture experiments, utilizing stem cell differentiation protocols and CRISPR-based gene editing to manipulate and study megakaryocyte function performing innovative biochemical experiments, including advanced immunoblotting, to dissect key signaling pathways involved in megakaryocyte development presenting research findings at project meetings and conferences, and contribute to peer-reviewed publications a master’s degree in biochemistry, cell biology, molecular biology, hematology, or a related field a strong foundation in molecular and cellular biology, with hands-on experience in cell culture and techniques such as microscopy, flow cytometry, or Western blotting interest in bioinformatics, including single-cell RNA-seq data analysis, and computational skills, such as experience with data analysis tools (e.g., GraphPad) or programming languages like R, would be an advantage demonstrated scientific rigor, curiosity, and a willingness to learn and apply new methods strong motivation and communication skills with proficiency in written and spoken English demonstrated through a language exam, thesis work, publications, or conference presentations You will have access to cutting-edge laboratory facilities, including single-cell platforms, high-resolution imaging systems, and automated immunoblotting technologies. You will contribute to an exciting research project based on a recently discovered signaling pathway crucial for megakaryocyte maturation. You will receive comprehensive training in molecular, cellular, and data analysis methods. We offer personalized mentoring and a collaborative environment designed to support your professional growth. This is what you can look forward to: training and continuing education retirement pension plan flexible working hours collegiality sport and fitness options employee events corporate benefits